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A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma
Complement component 5 (C5) has been described as either promoting or protecting against airway hyperresponsiveness (AHR) in experimental allergic asthma, suggesting pleomorphic effects of C5. Here we report that local pharmacological targeting of the C5a receptor (C5aR) prior to initial allergen se...
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Главные авторы: | , , , , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Clinical Investigation
2006
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386108/ https://ncbi.nlm.nih.gov/pubmed/16511606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26582 |
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