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IL-21 Receptor Signaling Partially Mediates Th2-Mediated Allergic Airway Responses

BACKGROUND: Interleukin-21 (IL-21) has been implicated in the development of Th2-mediated immune responses; however, the exact role it plays in allergic diseases is not well understood. OBJECTIVE: To elucidate the contribution of IL-21 receptor signaling to Th2-dependent immune responses in the lung...

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Autors principals: Lajoie, Stephane, Lewkowich, Ian, Herman, Nancy S., Sproles, Alyssa, Pesce, John T., Wynn, Thomas A., Grusby, Michael J., Hamid, Qutayba, Wills-Karp, Marsha
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083497/
https://ncbi.nlm.nih.gov/pubmed/24807637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12341
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