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Optimizing Cationic and Neutral Lipids for Efficient Gene Delivery at High Serum Content
BACKGROUND: Cationic liposome (CL)-DNA complexes are promising gene delivery vectors with potential applications in gene therapy. A key challenge in creating CL-DNA complexes for applications is that their transfection efficiency (TE) is adversely affected by serum. In particular, little is known ab...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051313/ https://ncbi.nlm.nih.gov/pubmed/24753287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2762 |
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