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Reprogramming the Methylome: Erasing Memory and Creating Diversity

The inheritance of epigenetic marks, in particular DNA methylation, provides a molecular memory that ensures faithful commitment to transcriptional programs during mammalian development. Epigenetic reprogramming results in global hypomethylation of the genome together with a profound loss of memory,...

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Autori principali: Lee, Heather J., Hore, Timothy A., Reik, Wolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051243/
https://ncbi.nlm.nih.gov/pubmed/24905162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.008
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