Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A(2A) receptor levels in rats subjected to neuroinflammation

BACKGROUND: Acetate supplementation reduces neuroglia activation and pro-inflammatory cytokine expression in rat models of neuroinflammation and Lyme neuroborreliosis. Because single-dose glyceryl triacetate (GTA) treatment increases brain phosphocreatine and reduces brain AMP levels, we postulate t...

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Detalhes bibliográficos
Main Authors: Smith, Mark D, Bhatt, Dhaval P, Geiger, Jonathan D, Rosenberger, Thad A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050445/
https://ncbi.nlm.nih.gov/pubmed/24898794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-99
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