Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation

BACKGROUND: Long-term acetate supplementation reduces neuroglial activation and cholinergic cell loss in a rat model of lipopolysaccharide-induced neuroinflammation. Additionally, a single dose of glyceryl triacetate, used to induce acetate supplementation, increases histone H3 and H4 acetylation an...

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Bibliographic Details
Main Authors: Soliman, Mahmoud L, Smith, Mark D, Houdek, Heidi M, Rosenberger, Thad A
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317831/
https://ncbi.nlm.nih.gov/pubmed/22413888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-51
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