Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation

BACKGROUND: Long-term acetate supplementation reduces neuroglial activation and cholinergic cell loss in a rat model of lipopolysaccharide-induced neuroinflammation. Additionally, a single dose of glyceryl triacetate, used to induce acetate supplementation, increases histone H3 and H4 acetylation an...

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Detalhes bibliográficos
Main Authors: Soliman, Mahmoud L, Smith, Mark D, Houdek, Heidi M, Rosenberger, Thad A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317831/
https://ncbi.nlm.nih.gov/pubmed/22413888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-51
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