Acetate supplementation reduces microglia activation and brain interleukin-1β levels in a rat model of Lyme neuroborreliosis

BACKGROUND: We have found that acetate supplementation significantly reduces neuroglia activation and pro-inflammatory cytokine release in a rat model of neuroinflammation induced with lipopolysaccharide. To test if the anti-inflammatory effect of acetate supplementation is specific to a TLR4-mediat...

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Autores principales: Brissette, Catherine A, Houdek, Heidi M, Floden, Angela M, Rosenberger, Thad A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520777/
https://ncbi.nlm.nih.gov/pubmed/23134838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-249
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