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In vivo siRNA delivery system for targeting to the liver by poly-l-glutamic acid-coated lipoplex()
In this study, we developed anionic polymer-coated liposome/siRNA complexes (lipoplexes) with chondroitin sulfate C (CS), poly-l-glutamic acid (PGA) and poly-aspartic acid (PAA) for siRNA delivery by intravenous injection, and evaluated the biodistribution and gene silencing effect in mice. The size...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050376/ https://ncbi.nlm.nih.gov/pubmed/25756001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinphs.2014.01.001 |
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