In vivo siRNA delivery system for targeting to the liver by poly-l-glutamic acid-coated lipoplex()

In this study, we developed anionic polymer-coated liposome/siRNA complexes (lipoplexes) with chondroitin sulfate C (CS), poly-l-glutamic acid (PGA) and poly-aspartic acid (PAA) for siRNA delivery by intravenous injection, and evaluated the biodistribution and gene silencing effect in mice. The size...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hattori, Yoshiyuki, Nakamura, Ayako, Arai, Shohei, Nishigaki, Mayu, Ohkura, Hiroyuki, Kawano, Kumi, Maitani, Yoshie, Yonemochi, Etsuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050376/
https://ncbi.nlm.nih.gov/pubmed/25756001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinphs.2014.01.001
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