Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions

Pluripotent stem cells are a promising tool for mechanistic studies of tissue development, drug screening, and cell-based therapies. Here, we report an effective and mass-producing strategy for the stepwise differentiation of mouse embryonic stem cells (mESCs) and mouse and human induced pluripotent...

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Autors principals: Kanke, Kosuke, Masaki, Hideki, Saito, Taku, Komiyama, Yuske, Hojo, Hironori, Nakauchi, Hiromitsu, Lichtler, Alexander C., Takato, Tsuyoshi, Chung, Ung-il, Ohba, Shinsuke
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050355/
https://ncbi.nlm.nih.gov/pubmed/24936463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.04.016
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