Heterochromatin Dynamics during the Differentiation Process Revealed by the DNA Methylation Reporter Mouse, MethylRO

In mammals, DNA is methylated at CpG sites, which play pivotal roles in gene silencing and chromatin organization. Furthermore, DNA methylation undergoes dynamic changes during development, differentiation, and in pathological processes. The conventional methods represent snapshots; therefore, the d...

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Hauptverfasser: Ueda, Jun, Maehara, Kazumitsu, Mashiko, Daisuke, Ichinose, Takako, Yao, Tatsuma, Hori, Mayuko, Sato, Yuko, Kimura, Hiroshi, Ohkawa, Yasuyuki, Yamagata, Kazuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050349/
https://ncbi.nlm.nih.gov/pubmed/24936475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.008
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