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Heterochromatin Dynamics during the Differentiation Process Revealed by the DNA Methylation Reporter Mouse, MethylRO

In mammals, DNA is methylated at CpG sites, which play pivotal roles in gene silencing and chromatin organization. Furthermore, DNA methylation undergoes dynamic changes during development, differentiation, and in pathological processes. The conventional methods represent snapshots; therefore, the d...

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Detalhes bibliográficos
Main Authors: Ueda, Jun, Maehara, Kazumitsu, Mashiko, Daisuke, Ichinose, Takako, Yao, Tatsuma, Hori, Mayuko, Sato, Yuko, Kimura, Hiroshi, Ohkawa, Yasuyuki, Yamagata, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050349/
https://ncbi.nlm.nih.gov/pubmed/24936475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.008
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