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Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation
A greater understanding of the regulatory mechanisms that govern γ-globin expression in humans, especially the switching from γ- to β-globin, which occurs after birth, would help to identify new therapeutic targets for patients with β-hemoglobinopathy. To further elucidate the mechanisms involved in...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050337/ https://ncbi.nlm.nih.gov/pubmed/22267339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199356 |
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