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Recent advances in globin research using genome-wide association studies and gene editing

A long-sought goal in the hemoglobin field has been an improved understanding of the mechanisms that regulate the switch from fetal (HbF) to adult (HbA) hemoglobin during development. With such knowledge, the hope is that strategies for directed reactivation of HbF in adults could be devised as an a...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Autor principal: Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870148/
https://ncbi.nlm.nih.gov/pubmed/26866328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13001
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