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Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?

Muscle force is typically proportional to muscle size, resulting in constant force normalized to muscle fiber cross-sectional area (specific force). Mice overexpressing insulin-like growth factor-1 (IGF-1) exhibit a proportional gain in muscle force and size, but not the myostatin-deficient mice. In...

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Main Authors: Qaisar, Rizwan, Renaud, Guillaume, Morine, Kevin, Barton, Elisabeth R., Sweeney, H. Lee, Larsson, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050333/
https://ncbi.nlm.nih.gov/pubmed/22125316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-192195
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