Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness

Sepsis is associated with impaired muscle function but the role of glucocorticoids in sepsis-induced muscle weakness is not known. We tested the role of glucocorticoids in sepsis-induced muscle weakness by treating septic rats with the glucocorticoid receptor antagonist RU38486. In addition, normal...

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Detalhes bibliográficos
Main Authors: Alamdari, Nima, Toraldo, Gianluca, Aversa, Zaira, Smith, Ira, Castillero, Estibaliz, Renaud, Guillaume, Qaisar, Rizwan, Larsson, Lars, Jasuja, Ravi, Hasselgren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Physical Activity and Inactivity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517670/
https://ncbi.nlm.nih.gov/pubmed/23019215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00636.2011
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