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The roles of toxin A and toxin B in Clostridium difficile infection: Insights from the gnotobiotic piglet model

We recently published our findings indicating that anti-TcdB antibodies were effective as treatment for C. difficile infection, but that anti-TcdA actually worsened prognosis in the gnotobiotic piglet model. To further investigate the roles of the two toxins, we administered purified toxins separate...

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Bibliographic Details
Main Authors: Steele, Jennifer, Parry, Nicola, Tzipori, Saul
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049938/
https://ncbi.nlm.nih.gov/pubmed/24394234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.26855
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