Caricamento...

Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system

Labeling and tracing of specific sequences in living cells has been a major challenge in studying the spatiotemporal dynamics of native chromatin. Here we repurposed the prokaryotic CRISPR/Cas adaptive immunity system to specifically detect endogenous genomic loci in mouse embryonic stem cells. We c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Anton, Tobias, Bultmann, Sebastian, Leonhardt, Heinrich, Markaki, Yolanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049922/
https://ncbi.nlm.nih.gov/pubmed/24637835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.28488
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !