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The quest to overcome resistance to EGFR-targeted therapies in cancer

All patients with metastatic lung, colorectal, pancreatic or head and neck cancers who initially benefit from epidermal growth factor receptor (EGFR)-targeted therapies eventually develop resistance. An increasing understanding of the number and complexity of resistance mechanisms highlights the Her...

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Detalhes bibliográficos
Main Authors: Chong, Curtis R, Jänne, Pasi A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049336/
https://ncbi.nlm.nih.gov/pubmed/24202392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3388
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