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Palladium-Catalyzed Hydroxylation of Aryl and Heteroaryl Halides Enabled by the Use of a Palladacycle Precatalyst

[Image: see text] A method for the hydroxylation of aryl and heteroaryl halides, promoted by a catalyst based on a biarylphosphine ligand tBuBrettPhos (L5) and its corresponding palladium precatalyst (1), is described. The reactions allow the cross-coupling of both potassium and cesium hydroxides wi...

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Autores principales: Cheung, Chi Wai, Buchwald, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049244/
https://ncbi.nlm.nih.gov/pubmed/24762125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500662s
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