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Protective Role of CYP2E1 Inhibitor Diallyl Disulfide (DADS) on Alcohol Induced Malondialdehyde-Deoxyguanosine (M1dG) Adduct Formation

BACKGROUND: Alcohol use disorders are often associated with lung disease. Alcohol exposure leads to the production of reactive oxygen species, lipid peroxidation, and formation of malondialdehyde (MDA) as well as induce the expression of cytochrome p450 2E1 (CYP2E1). Likewise, cigarette smoking can...

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Detalhes bibliográficos
Main Authors: Sapkota, M., Hottor, T. K., DeVasure, J. M., Wyatt, T. A., McCaskill, M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049196/
https://ncbi.nlm.nih.gov/pubmed/24891074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12439
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