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Malondialdehyde-acetaldehyde (MAA) adducted surfactant protein induced lung inflammation is mediated through scavenger receptor a (SR-A1)

BACKGROUND: Co-exposure to cigarette smoke and alcohol leads to the generation of high concentrations of acetaldehyde and malondialdehyde in the lung. These aldehydes being highly electrophilic in nature react with biologically relevant proteins such as surfactant protein D (SPD) through a Schiff ba...

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Bibliografski detalji
Izdano u:Respir Res
Glavni autori: Sapkota, Muna, DeVasure, Jane M., Kharbanda, Kusum K., Wyatt, Todd A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307820/
https://ncbi.nlm.nih.gov/pubmed/28193223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0517-x
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