Malondialdehyde-acetaldehyde protein adducts are found exclusively in the lungs of smokers with alcohol use disorders and are associated with systemic anti-MAA antibodies

BACKGROUND: Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUD) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a stable protein adduct,...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Sapkota, Muna, Burnham, Ellen L., DeVasure, Jane M., Sweeter, Jenea M., Hunter, C.D., Duryee, Michael J., Klassen, Lynell W., Kharbanda, Kusum K., Sisson, Joseph H., Thiele, Geoffrey M., Wyatt, Todd A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711572/
https://ncbi.nlm.nih.gov/pubmed/28941289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13509
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