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Protective Role of CYP2E1 Inhibitor Diallyl Disulfide (DADS) on Alcohol Induced Malondialdehyde-Deoxyguanosine (M1dG) Adduct Formation

BACKGROUND: Alcohol use disorders are often associated with lung disease. Alcohol exposure leads to the production of reactive oxygen species, lipid peroxidation, and formation of malondialdehyde (MDA) as well as induce the expression of cytochrome p450 2E1 (CYP2E1). Likewise, cigarette smoking can...

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Hlavní autoři: Sapkota, M., Hottor, T. K., DeVasure, J. M., Wyatt, T. A., McCaskill, M. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049196/
https://ncbi.nlm.nih.gov/pubmed/24891074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12439
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