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PKA-Phosphorylated K(V)1 Channels in PSD95 Signaling Complex Contribute to the Resting Membrane Potential and Diameter of Cerebral Arteries

RATIONALE: Postsynaptic density-95 (PSD95) is a scaffolding protein that associates with voltage-gated, Shaker-type K(+) (K(V)1) channels and promotes the expression of K(V)1 channels in vascular smooth muscle cells (cVSMCs) of the cerebral circulation. However, the physiological role of PSD95 in me...

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Библиографические подробности
Главные авторы: Moore, Christopher L., Nelson, Piper L., Parelkar, Nikhil K., Rusch, Nancy J., Rhee, Sung W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049098/
https://ncbi.nlm.nih.gov/pubmed/24585759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.303167
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