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Distinct Structural Requirements for Clustering and Immobilization of K(+) Channels by PSD-95

PDZ-domain–containing proteins such as PSD-95 have been implicated in the targeting and clustering of membrane proteins. Biochemical and immunohistochemical studies indicate that PSD-95 recognizes COOH-terminal S/TXV sequences present in Kv1 K(+) channels. However, the effect of binding a PDZ domain...

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Bibliographic Details
Main Authors: Burke, Nancy A., Takimoto, Koichi, Li, Danqing, Han, Weiping, Watkins, Simon C., Levitan, Edwin S.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222984/
https://ncbi.nlm.nih.gov/pubmed/9874689
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