Beta1-adrenergic receptor-mediated dilation of rat cerebral artery requires Shaker-type K(V)1 channels on PSD95 scaffold

Postsynaptic density-95 (PSD95) is a scaffolding protein in cerebral vascular smooth muscle cells (cVSMCs), which binds to Shaker-type K(+) (K(V)1) channels and facilitates channel opening through phosphorylation by protein kinase A. β1-Adrenergic receptors (β1ARs) also have a binding motif for PSD9...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Moore, Christopher L, McClenahan, Samantha J, Hanvey, Hillary M, Jang, Dae-Song, Nelson, Piper L, Joseph, Biny K, Rhee, Sung W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640345/
https://ncbi.nlm.nih.gov/pubmed/25966954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.91
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