The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

Cyclophosphamide is one of several clinically important cancer drugs whose therapeutic efficacy is due in part to their ability to stimulate anti-tumor immune responses. Studying mouse models, we demonstrate that cyclophosphamide alters the composition of microbiota in the small intestine and induce...

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Detalhes bibliográficos
Main Authors: Viaud, Sophie, Saccheri, Fabiana, Mignot, Grégoire, Yamazaki, Takahiro, Daillère, Romain, Hannani, Dalil, Enot, David P., Pfirschke, Christina, Engblom, Camilla, Pittet, Mikael J., Schlitzer, Andreas, Ginhoux, Florent, Apetoh, Lionel, Chachaty, Elisabeth, Woerther, Paul-Louis, Eberl, Gérard, Bérard, Marion, Ecobichon, Chantal, Clermont, Dominique, Bizet, Chantal, Gaboriau-Routhiau, Valérie, Cerf-Bensussan, Nadine, Opolon, Paule, Yessaad, Nadia, Vivier, Eric, Ryffel, Bernhard, Elson, Charles O., Doré, Joël, Kroemer, Guido, Lepage, Patricia, Boneca, Ivo Gomperts, Ghiringhelli, François, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048947/
https://ncbi.nlm.nih.gov/pubmed/24264990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240537
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