The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

Cyclophosphamide is one of several clinically important cancer drugs whose therapeutic efficacy is due in part to their ability to stimulate anti-tumor immune responses. Studying mouse models, we demonstrate that cyclophosphamide alters the composition of microbiota in the small intestine and induce...

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主要な著者: Viaud, Sophie, Saccheri, Fabiana, Mignot, Grégoire, Yamazaki, Takahiro, Daillère, Romain, Hannani, Dalil, Enot, David P., Pfirschke, Christina, Engblom, Camilla, Pittet, Mikael J., Schlitzer, Andreas, Ginhoux, Florent, Apetoh, Lionel, Chachaty, Elisabeth, Woerther, Paul-Louis, Eberl, Gérard, Bérard, Marion, Ecobichon, Chantal, Clermont, Dominique, Bizet, Chantal, Gaboriau-Routhiau, Valérie, Cerf-Bensussan, Nadine, Opolon, Paule, Yessaad, Nadia, Vivier, Eric, Ryffel, Bernhard, Elson, Charles O., Doré, Joël, Kroemer, Guido, Lepage, Patricia, Boneca, Ivo Gomperts, Ghiringhelli, François, Zitvogel, Laurence
フォーマット: Artigo
言語:Inglês
出版事項: 2013
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048947/
https://ncbi.nlm.nih.gov/pubmed/24264990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240537
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