The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

Cyclophosphamide is one of several clinically important cancer drugs whose therapeutic efficacy is due in part to their ability to stimulate anti-tumor immune responses. Studying mouse models, we demonstrate that cyclophosphamide alters the composition of microbiota in the small intestine and induce...

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Bibliografische gegevens
Hoofdauteurs: Viaud, Sophie, Saccheri, Fabiana, Mignot, Grégoire, Yamazaki, Takahiro, Daillère, Romain, Hannani, Dalil, Enot, David P., Pfirschke, Christina, Engblom, Camilla, Pittet, Mikael J., Schlitzer, Andreas, Ginhoux, Florent, Apetoh, Lionel, Chachaty, Elisabeth, Woerther, Paul-Louis, Eberl, Gérard, Bérard, Marion, Ecobichon, Chantal, Clermont, Dominique, Bizet, Chantal, Gaboriau-Routhiau, Valérie, Cerf-Bensussan, Nadine, Opolon, Paule, Yessaad, Nadia, Vivier, Eric, Ryffel, Bernhard, Elson, Charles O., Doré, Joël, Kroemer, Guido, Lepage, Patricia, Boneca, Ivo Gomperts, Ghiringhelli, François, Zitvogel, Laurence
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048947/
https://ncbi.nlm.nih.gov/pubmed/24264990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240537
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