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Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle

Airway smooth muscle (ASM) contraction is an important component of the pathophysiology of asthma. Taurine, an agonist of glycine receptor chloride (GlyR Cl(−)) channels, was found to relax contracted ASM, which led us to question whether functional GlyR Cl(−) channels are expressed in ASM. Messenge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yim, Peter D., Gallos, George, Xu, Dingbang, Zhang, Yi, Emala, Charles W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048936/
https://ncbi.nlm.nih.gov/pubmed/21282206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-170530
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