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The Effect of UGT1A and UGT2B Polymorphisms on Colorectal Cancer Risk: Haplotype Associations and Gene-Environment Interactions

UDP-glucuronosyltransferases (UGTs) play an important role in the phase II metabolism of exogenous and endogenous compounds. As colorectal cancer (CRC) etiology is thought to involve the biotransformation of dietary factors, UGT polymorphisms may affect CRC risk by altering levels of exposure. Genot...

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Detalhes bibliográficos
Main Authors: Angstadt, Andrea Y., Hartman, Terryl J., Lesko, Samuel M., Muscat, Joshua E., Zhu, Junjia, Gallagher, Carla J., Lazarus, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048880/
https://ncbi.nlm.nih.gov/pubmed/24822274
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