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Increased Mitochondrial Electron Transport Chain Activity at Complex I Is Regulated by N-Acetylcysteine in Lymphocytes of Patients with Systemic Lupus Erythematosus

Aims: Systemic lupus erythematosus (SLE) patients' peripheral blood lymphocytes (PBL) show mitochondrial dysfunction and oxidative stress. To determine the electrochemical bases of mitochondrial dysfunction, we measured electron transport chain (ETC) activity and its regulation by N-acetylcyste...

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Main Authors: Doherty, Edward, Oaks, Zachary, Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048573/
https://ncbi.nlm.nih.gov/pubmed/24673154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5702
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