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Metabolic control of the epigenome in systemic Lupus erythematosus
Epigenetic mechanisms are proposed to underlie aberrant gene expression in systemic lupus erythematosus (SLE) that results in dysregulation of the immune system and loss of tolerance. Modifications of DNA and histones require substrates derived from diet and intermediary metabolism. DNA and histone...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034124/ https://ncbi.nlm.nih.gov/pubmed/24128087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2013.834495 |
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