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Increased Mitochondrial Electron Transport Chain Activity at Complex I Is Regulated by N-Acetylcysteine in Lymphocytes of Patients with Systemic Lupus Erythematosus

Aims: Systemic lupus erythematosus (SLE) patients' peripheral blood lymphocytes (PBL) show mitochondrial dysfunction and oxidative stress. To determine the electrochemical bases of mitochondrial dysfunction, we measured electron transport chain (ETC) activity and its regulation by N-acetylcyste...

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Detalhes bibliográficos
Main Authors: Doherty, Edward, Oaks, Zachary, Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048573/
https://ncbi.nlm.nih.gov/pubmed/24673154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5702
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