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Increased Mitochondrial Electron Transport Chain Activity at Complex I Is Regulated by N-Acetylcysteine in Lymphocytes of Patients with Systemic Lupus Erythematosus

Aims: Systemic lupus erythematosus (SLE) patients' peripheral blood lymphocytes (PBL) show mitochondrial dysfunction and oxidative stress. To determine the electrochemical bases of mitochondrial dysfunction, we measured electron transport chain (ETC) activity and its regulation by N-acetylcyste...

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Bibliographic Details
Main Authors: Doherty, Edward, Oaks, Zachary, Perl, Andras
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048573/
https://ncbi.nlm.nih.gov/pubmed/24673154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5702
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