Generation of a novel therapeutic peptide that depletes MDSC in tumor-bearing mice

Cancer immune evasion is an emerging hallmark of disease progression. Functional studies to understand the role of myeloid-derived suppressor cells (MDSC) in the tumor microenvironment however, are limited by the lack of available specific cell surface markers. We adapted a competitive peptide phage...

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Hauptverfasser: Qin, Hong, Lerman, Beatrisa, Sakamaki, Ippei, Wei, Guowei, Cha, Soungchul, Rao, Sheetal S., Qian, Jianfei, Hailemichael, Yared, Nurieva, Roza, Dwyer, Karen C., Roth, Johannes, Yi, Qing, Overwijk, Willem W., Kwak, Larry W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048321/
https://ncbi.nlm.nih.gov/pubmed/24859530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3560
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