Lenalidomide enhances the curative effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas

Immunomodulatory drugs (IMiDs) are effective therapeutic agents with direct inhibitory effects on malignant B- and plasma cells and immunomodulatory effects on the T cell activation. This dual function of IMiDs makes them appealing candidates for combination with an cancer vaccine. We investigated t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Leukemia
Prif Awduron: Sakamaki, Ippei, Kwak, Larry W., Cha, Soung-chul, Yi, Qing, Lerman, Beatrisa, Chen, Jian, Surapaneni, Sekhar, Bateman, Scott, Qin, Hong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581849/
https://ncbi.nlm.nih.gov/pubmed/23765229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.177
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