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Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H(2)O(2)-Induced 5-Lipoxygenase
Pulmonary Hypertension (PH) is a progressive disorder characterized by endothelial dysfunction and proliferation. Hypoxia induces PH by increasing vascular remodeling. A potential mediator in hypoxia-induced PH development is arachidonate 5-Lipoxygenase (ALOX5). While ALOX5 metabolites have been sho...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048210/ https://ncbi.nlm.nih.gov/pubmed/24906007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098532 |
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