Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP

Disturbance of endoplasmic reticulum (ER) homeostasis causes ER stress and leads to activation of the unfolded protein response, which reduces the stress and promotes cell survival at the early stage of stress, or triggers cell death and apoptosis when homeostasis is not restored under prolonged ER...

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Detalhes bibliográficos
Main Authors: Chen, L, Xu, S, Liu, L, Wen, X, Xu, Y, Chen, J, Teng, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047922/
https://ncbi.nlm.nih.gov/pubmed/24810055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.193
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