The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa

Retinitis pigmentosa (RP) is a group of inherited diseases that cause blindness due to the progressive death of rod and cone photoreceptors in the retina. There are currently no effective treatments for RP. Inherited mutations in rhodopsin, the light-sensing protein of rod photoreceptor cells, are t...

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Hlavní autoři: Parfitt, D A, Aguila, M, McCulley, C H, Bevilacqua, D, Mendes, H F, Athanasiou, D, Novoselov, S S, Kanuga, N, Munro, P M, Coffey, P J, Kalmar, B, Greensmith, L, Cheetham, M E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047904/
https://ncbi.nlm.nih.gov/pubmed/24853414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.214
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