The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption

Metastasis accounts for most deaths from breast cancer, driving the need for new therapeutics that can impede disease progression. Rationally designed peptides that take advantage of cancer-specific differences in cellular physiology are an emerging technology that offer promise as a treatment for m...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, M W, Bassiouni, R, Sparrow, N A, Iketani, A, Boohaker, R J, Moskowitz, C, Vishnubhotla, P, Khaled, A S, Oyer, J, Copik, A, Fernandez-Valle, C, Perez, J M, Khaled, A R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047892/
https://ncbi.nlm.nih.gov/pubmed/24853427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.225
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