The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption

Metastasis accounts for most deaths from breast cancer, driving the need for new therapeutics that can impede disease progression. Rationally designed peptides that take advantage of cancer-specific differences in cellular physiology are an emerging technology that offer promise as a treatment for m...

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Autori principali: Lee, M W, Bassiouni, R, Sparrow, N A, Iketani, A, Boohaker, R J, Moskowitz, C, Vishnubhotla, P, Khaled, A S, Oyer, J, Copik, A, Fernandez-Valle, C, Perez, J M, Khaled, A R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047892/
https://ncbi.nlm.nih.gov/pubmed/24853427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.225
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