Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression

Estrogen receptor-alpha positive (ER(+)) breast cancers comprise the majority of human breast cancers, but molecular mechanisms underlying this subtype of breast cancers remain poorly understood. Here, we show that ER(+) mammary luminal tumors arising in Tip30(−/−)MMTV-Neu mice exhibited increased e...

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Bibliographische Detailangaben
Hauptverfasser: Chen, F, Li, A, Gao, S, Hollern, D, Williams, M, Liu, F, VanSickle, E A, Andrechek, E, Zhang, C, Yang, C, Luo, R, Xiao, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047867/
https://ncbi.nlm.nih.gov/pubmed/24853420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.224
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