ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway

Activin receptor-like kinase 1 (ALK1) is an endothelial-specific member of the TGF-β/BMP receptor family that is inactivated in patients with hereditary hemorrhagic telangiectasia (HHT). How ALK1 signaling regulates angiogenesis remains incompletely understood. Here we show that ALK1 inhibits angiog...

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Bibliographic Details
Main Authors: Larrivée, Bruno, Prahst, Claudia, Gordon, Emma, del Toro, Raquel, Mathivet, Thomas, Duarte, Antonio, Simons, Michael, Eichmann, Anne
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047762/
https://ncbi.nlm.nih.gov/pubmed/22421041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.005
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