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ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway
Activin receptor-like kinase 1 (ALK1) is an endothelial-specific member of the TGF-β/BMP receptor family that is inactivated in patients with hereditary hemorrhagic telangiectasia (HHT). How ALK1 signaling regulates angiogenesis remains incompletely understood. Here we show that ALK1 inhibits angiog...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047762/ https://ncbi.nlm.nih.gov/pubmed/22421041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.005 |
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