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Pharmacokinetics of Artesunate Alone and in Combination with Sulfadoxine/Pyrimethamine in Healthy Sudanese Volunteers

Artesunate (AS) in combination with sulfadoxine/pyrimethamine (SP) is the first-line therapy for management of uncomplicated Plasmodium falciparum malaria in Sudan. The objective of this study was to assess the potential impact of SP on the pharmacokinetics of AS and its active metabolite, dihydroar...

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Detalhes bibliográficos
Main Authors: Matar, Kamal M., Awad, Abdelmoneim I., Elamin, Sakina B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047733/
https://ncbi.nlm.nih.gov/pubmed/24615137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.13-0283
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