Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda

BACKGROUND: A pre-packaged fixed-dose formulation of chloroquine (CQ) and sulfadoxine/pyrimethamine (S/P) combination (Homapak) is widely used for the treatment of falciparum malaria in Ugandan children. It is however a product whose pharmacokinetics and interactions have not been studied. OBJECTIVE...

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Main Authors: Obua, C, Ntale, M S, Lundblad, MS, Mahindi, M, Gustafsson, LL, Ogwal-Okeng, JW, Anokbonggo, W W, Hellgren, U
Formato: Artigo
Idioma:Inglês
Publicado em: Makerere Medical School 2006
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831981/
https://ncbi.nlm.nih.gov/pubmed/16916298
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