A Caenorhabditis elegans–based assay recognizes immunoglobulin light chains causing heart amyloidosis

Poor prognosis and limited therapeutic options characterize immunoglobulin light-chain (AL) amyloidosis with major heart involvement. Reliable experimental models are needed to study light-chain (LC)/heart interactions and to explore strategies for prevention of cardiac damage. We have exploited the...

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Main Authors: Diomede, Luisa, Rognoni, Paola, Lavatelli, Francesca, Romeo, Margherita, del Favero, Elena, Cantù, Laura, Ghibaudi, Elena, di Fonzo, Andrea, Corbelli, Alessandro, Fiordaliso, Fabio, Palladini, Giovanni, Valentini, Veronica, Perfetti, Vittorio, Salmona, Mario, Merlini, Giampaolo
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Plenary Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047494/
https://ncbi.nlm.nih.gov/pubmed/24665135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-525634
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