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Haptoglobin Genotype-dependent Differences in Macrophage Lysosomal Oxidative Injury
The major function of the Haptoglobin (Hp) protein is to control trafficking of extracorpuscular hemoglobin (Hb) thru the macrophage CD163 receptor with degradation of the Hb in the lysosome. There is a common copy number polymorphism in the Hp gene (Hp 2 allele) that has been associated with a seve...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047400/ https://ncbi.nlm.nih.gov/pubmed/24778180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554212 |
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