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Haptoglobin Genotype-dependent Differences in Macrophage Lysosomal Oxidative Injury
The major function of the Haptoglobin (Hp) protein is to control trafficking of extracorpuscular hemoglobin (Hb) thru the macrophage CD163 receptor with degradation of the Hb in the lysosome. There is a common copy number polymorphism in the Hp gene (Hp 2 allele) that has been associated with a seve...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047400/ https://ncbi.nlm.nih.gov/pubmed/24778180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554212 |
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