Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus

The haptoglobin (Hp) genotype is a major determinant of progression of nephropathy in individuals with diabetes mellitus (DM). The major function of the Hp protein is to bind and modulate the fate of extracorpuscular hemoglobin and its iron cargo. We have previously demonstrated an interaction betwe...

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Библиографические подробности
Главные авторы: Asleh, Rabea, Nakhoul, Farid M., Miller-Lotan, Rachel, Awad, Hoda, Farbstein, Dan, Levy, Nina S., Nakhoul, Nakhoul, Iancu, Theodore C., Manov, Irena, Laue, Michael, Traber, Maret G., Lebold, Katie M., Levy, Andrew P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600120/
https://ncbi.nlm.nih.gov/pubmed/22749805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.06.015
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