Poly(ADP-ribose) Polymerase 1 (PARP1) Associates with E3 Ubiquitin-Protein Ligase UHRF1 and Modulates UHRF1 Biological Functions

Poly(ADP-ribose) polymerase 1 (PARP1, also known as ARTD1) is an abundant nuclear enzyme that plays important roles in DNA repair, gene transcription, and differentiation through the modulation of chromatin structure and function. In this work we identify a physical and functional poly(ADP-ribose)-m...

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Detalhes bibliográficos
Main Authors: De Vos, Mike, El Ramy, Rosy, Quénet, Delphine, Wolf, Patricia, Spada, Fabio, Magroun, Najat, Babbio, Federica, Schreiber, Valérie, Leonhardt, Heinrich, Bonapace, Ian Marc, Dantzer, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047392/
https://ncbi.nlm.nih.gov/pubmed/24782312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527424
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